Human disease genetics
Genome-wide association and sequencing studies in large clinical and population cohorts, to identify the variants and genes that carry risk for neurological disorders.
Genomics of the brain and its disorders
We study how genetic variation shapes the nervous system — and how that knowledge can be turned into better diagnosis and treatment of neurological disease. Our work spans large-scale human genetics, multi-omics and deep clinical phenotyping.
Research
Neurological disease is common, heritable and mechanistically poorly understood. We work across four connected themes to close that gap.
Genome-wide association and sequencing studies in large clinical and population cohorts, to identify the variants and genes that carry risk for neurological disorders.
Transcriptomics, methylation and proteomics layered onto genetic signals, so that an associated locus becomes a candidate gene, tissue and pathway rather than a coordinate.
Nationwide registries, hospital records and digital measures of cognition and symptom burden — phenotypes precise enough for the genetics to resolve.
Turning findings into usable tools: risk stratification, biomarkers and drug-target evidence that can be tested in the clinic.
Team
Publications
Newest first, compiled automatically from the group members' ORCID records and Crossref metadata.
Funding & collaborators
Contact
We welcome collaborations, and we are always glad to hear from prospective PhD students and postdocs with an interest in the genetics of neurological disease — write to us with a CV and a short note on what you would like to work on.